Lactobacillus rhamnosus GG is one of the most vigorously studied probiotic strains, with over 800 studies conducted to date. Its ability to resist stomach acid and intestinal bile degradation allows it to survive in the body longer than most other probiotics, thereby increasing its potential of offering health advantages to the host. Several studies suggested that it may help improve the intestinal wall barrier, which could reinforce the immune system. Its immune-modifying properties inspired a number of studies to explore its benefits for GI illnesses, including studies that revealed it can decrease the frequency of antibiotic induced diarrhea and that it can benefit subjects with Irritable Bowel Syndrome (IBS) symptoms.
Bifidobacterium probiotic species play a key role in gut activity and in the immune system. In fact, they are among the first microbes to colonize our digestive tract as infants. They're routinely added to functional foods as active ingredients because of their potential health benefits for the digestive system. Bifidobacterium lactis HN019 is known for its ability to promote gut motility - it can be helpful for people with bowel movement issues and has been shown to improve functional gastrointestinal symptoms (or constipation) in certain populations. It may also improve immune function, and other bifidobacterium species are being studied for their potential ability to support neurocognition and reduce stress.
FUN FACT: Consumption of red wine can lead to an increase in gut bifidobacteria!
Bifidobacterium longum is well-suited for intestinal survival and is known for its ability to promote microbial diversity. This bacteria has properties making it resistant to acidic conditions, enabling it to adhere to intestinal walls - a necessary property to survive the journey down the gastrointestinal tract and confer health benefits on the body. Some studies have further argued that the ability of the BI-05 strain to adhere to the intestinal wall and reside longer in the digestive system may enable it to favorably regulate immune responses, potentially strengthening the body’s response to hostile (or bad) bacteria. Other studies have also suggested that it may modulate brain activity and potentially reduce the negative impact of social stresses.
FUN FACT: it is our most common gut bacteria in infancy, comprising over 90% of the probiotics in our body!
Bacillus subtilis is known for conferring strong benefits on digestive and general health thanks to a strong ability to survive in extreme environments. We use a genome-sequenced and clinically tested strain of Bacillus Subtilis with supported benefits for both digestive and immune health. Developed by our microbiome-specialized manufacturer, benefits such as controlling microbial populations in the gut and optimizing digestion have been supported by multiple human clinical studies. Studies have also revealed this probiotic strains’ ability to form spores that protect healthy microbes from harsh conditions, thereby enabling them to reach the GI tract where they can safely develop. Other studies have suggested that Bacillus Subtilis’ probiotic strains can improve bowel movements and reduce occasional constipation or diarrhea.
FUN FACT: Bacillus subtilis is also the bacterial species holding the record for surviving the longest in space -- 6 years on a NASA satellite!